This chapter mostly focused on and defined the main and important parameters with the liquid chromatography to the method development and optimization of an acceptable balance-indicating LC method and impurity profiling scientific tests. Each individual and every parameter which controls the purification of many of the organic and natural compounds

System suitability checks verify and be certain if the method’s performance is suitable at some time of research in accordance with the standards established forth while in the process or not. Process suitability parameters are preferred determined by the criticality of separation. Normally, resolution aspect for the two adjacent peaks or closely

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